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Shock vs Sepsis vs SIRS: Key Differentiators

​ 1. Definitions: Systemic Inflammatory Response Syndrome (SIRS) SIRS describes a non-specific systemic inflammatory state, triggered by infectious or non-infectious insults. SIRS Criteria (Traditional) Presence of ≥2 of: Temperature >38°C or <36°C Heart rate >90/min Respiratory rate >20/min or PaCO₂ <32 mmHg WBC >12,000 or <4,000 or >10% bands SIRS can occur in: Trauma Burns Pancreatitis Post-operative states Infections SIRS is not equivalent to infection. Sepsis (Sepsis-3 Definition) According to the Surviving Sepsis Campaign and consensus definitions: Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to infection. Operationalized as: Suspected/confirmed infection Increase in SOFA score ≥2 Septic Shock A subset of sepsis characterized by: Persistent hypotension requiring vasopressors Serum lactate >2 mmol/L despite adequate fluid resuscitation This carries a mortality >40%. Sho...
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Pennsylvania Med Student Finds Forrest Fenn's Hidden Chest Of Treasure







Jonathan Stuef, A medical student from pennsylvania medical school has found a chest of treasure containing precious jewels and gold in the mountain forests of wstern United States which was hidden by an eccentric art and antiquities dealer Forrest Fenn. Jack said that this treasure become an attraction for people around the world and many of them died while finding it. the treasure is estimated to be worth millions. 

Deniel Barbarisi l, the author of a forthcoming book "Chasing the Thrill" which is based on this treasure hunt, said that few of who were hunting for the same alsi threatened Jack to hurt physically and legally, that is the reason why Jack had to move to a higher security home fir his protection. Jack Stuef said that the treasure is now at a secure location and he's planning to sell it to pay his student loans which seems reasonable for any health professional.

Forrest Fenn decided to hide this chest of treasure in woods because he always concerned that people spend most of their time staying inside. this might help people to get out if their home and search for it. Dal Neutzel who said this was one who was asked by Fenn to publish on his website about treasure being found. According to the Albuquerque Journal it was estimated that around 350,000 people went to search for this over the past ten years. 

Fenn Provided 9 clues to find this treasure in the form of a poem. Analysis shows that Fenn's treasure hunt was an extraordinary goal pursuits that can consume an individual over the time. A survay finding shows that approximately two million American adults were involved in the chase at some level including 433,000 competitive searchers having advanced knowledge.

This story looks like a thriller movie or a bigboss house in which different groups (initially friendly) made to fulfill a task which at the end gets more competitive and dangerous...??? May be....!! Share your ideas😃.

Source - Medscape, Springer
More info. - Article by Jack Stuef
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